Possible involvement of minor lysophospholipids in the increase in plasma lysophosphatidic acid in acute coronary syndrome.
- Authors
- Type
- Published Article
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Publisher
- Ovid Technologies Wolters Kluwer -American Heart Association
- Publication Date
- Feb 01, 2015
- Volume
- 35
- Issue
- 2
- Pages
- 463–470
- Identifiers
- DOI: 10.1161/ATVBAHA.114.304748
- PMID: 25425621
- Source
- Medline
- Keywords
- License
- Unknown
Abstract
Specific LPA species, especially long-chain unsaturated LPA, were elevated in ACS patients, along with the corresponding minor lysophospholipids. The elevation of these LPA species might be mainly caused by presently unidentified LPA-producing pathway(s). Minor lysophospholipids might be involved in the generation of LPA, especially 22:6 LPA, and in the pathogenesis of ACS.