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Positive end-expiratory pressure modifies response to recombinant and natural exogenous surfactant in ventilated immature newborn rabbits.

Authors
  • Hilgendorff, Anne
  • Reiss, Irwin
  • Ruppert, Clemens
  • Hanfstingl, Thilo
  • Seliger, Ann Sophie
  • Gunther, Andreas
  • Ebsen, Michael
  • Gortner, Ludwig
Type
Published Article
Journal
Biology of the neonate
Publication Date
Jan 01, 2006
Volume
90
Issue
3
Pages
210–216
Identifiers
PMID: 16763385
Source
Medline
License
Unknown

Abstract

Response to rSP-C surfactant depends on the PEEP level applied in our model of neonatal RDS. These findings should be considered for the conception of clinical trials regarding treatment strategies in neonatal RDS.

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