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Portal vein thrombosis in association with factor V Leiden mutation in a patient with hepatocellular carcinoma.

Authors
  • Gürgey, A
  • Büyükpamukcu, M
  • Baskut, C
  • Yalcin, B
  • Gögüş, S
Type
Published Article
Journal
Medical and pediatric oncology
Publication Date
Sep 01, 1997
Volume
29
Issue
3
Pages
224–225
Identifiers
PMID: 9212850
Source
Medline
License
Unknown

Abstract

We report a case of hepatocellular carcinoma associated with portal vein thrombosis. Analysis of whole cellular DNA demonstrated heterozygosity for the factor V Leiden mutation. The patient also had marked protein C deficiency. The presence of the mutation associated with protein C deficiency may increase the risk of thrombosis in this patient with hepatocellular carcinoma.

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