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Poor glycemic control is associated with reduced prostate specific antigen concentrations in men with type 1 diabetes.

Authors
  • Sarma, Aruna V1
  • Hotaling, James2
  • Dunn, Rodney L3
  • Cleary, Patricia A4
  • Braffett, Barbara H4
  • Kim, Catherine5
  • Martin, Catherine5
  • Herman, William5
  • Gatcomb, Patricia6
  • Jacobson, Alan M7
  • Holt, Sarah K8
  • Wessells, Hunter8
  • 1 Department of Urology, University of Michigan, Ann Arbor, Michigan. Electronic address: [email protected]
  • 2 Department of Surgery, University of Utah, Salt Lake City, Utah.
  • 3 Department of Urology, University of Michigan, Ann Arbor, Michigan.
  • 4 The Biostatistics Center, George Washington University, Washington, DC.
  • 5 Department of Medicine, University of Michigan, Ann Arbor, Michigan.
  • 6 Department of Medicine, Yale University, New Haven, Connecticut.
  • 7 Winthrop Research Institute, Winthrop-University Hospital, Mineola, New York.
  • 8 Department of Urology, University of Washington, Seattle, Washington.
Type
Published Article
Journal
The Journal of urology
Publication Date
March 2015
Volume
193
Issue
3
Pages
786–793
Identifiers
DOI: 10.1016/j.juro.2014.08.115
PMID: 25218922
Source
Medline
Keywords
License
Unknown

Abstract

Prostate specific antigen decreases as hemoglobin A1c increases in men with type 1 diabetes mellitus. This relationship is independent of age, body mass index, androgen levels, medication use and measures of diabetes severity, which suggests that factors related to glycemia may directly affect prostate specific antigen levels.

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