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Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use.

Authors
  • Trojahn Kølle, Stig-Frederik
  • Oliveri, Roberto S
  • Glovinski, Peter V
  • Kirchhoff, Maria
  • Mathiasen, Anders Bruun
  • Elberg, Jens Jørgen
  • Andersen, Peter Stemann
  • Drzewiecki, Krzysztof Tadeusz
  • Fischer-Nielsen, Anne
Type
Published Article
Journal
Cytotherapy
Publication Date
Sep 01, 2013
Volume
15
Issue
9
Pages
1086–1097
Identifiers
DOI: 10.1016/j.jcyt.2013.01.217
PMID: 23602579
Source
Medline
Keywords
License
Unknown

Abstract

We observed that the use of pHPL as a growth supplement for ASCs facilitated a significantly higher proliferation rate compared with FBS without compromising genomic stability or differentiation capacity.

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