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Polymorphisms of beta2-adrenergic receptor gene in serbian asthmatic adults: effects on response to Beta-agonists.

Authors
  • Petrovic-Stanojevic, Natasa
  • Topic, Aleksandra
  • Nikolic, Aleksandra
  • Stankovic, Marija
  • Dopudja-Pantic, Vesna
  • Milenkovic, Branislava
  • Radojkovic, Dragica
Type
Published Article
Journal
Molecular Diagnosis & Therapy
Publisher
Springer-Verlag
Publication Date
Dec 01, 2014
Volume
18
Issue
6
Pages
639–646
Identifiers
DOI: 10.1007/s40291-014-0116-1
PMID: 25074500
Source
Medline
License
Unknown

Abstract

We identified that in Serbian adults the 27Gln allele and 27Gln homozygosity are risk factors for asthma, which may be of clinical interest in disease prevention. The finding that younger carriers of the 27Gln allele respond better to LABA + ICS therapy may be utilized in personalized asthma treatment.

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