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Polymorphism at the TNF-alpha gene interacts with Mediterranean diet to influence triglyceride metabolism and inflammation status in metabolic syndrome patients: From the CORDIOPREV clinical trial.

Authors
  • Gomez-Delgado, Francisco1
  • Alcala-Diaz, Juan Francisco
  • Garcia-Rios, Antonio
  • Delgado-Lista, Javier
  • Ortiz-Morales, Ana
  • Rangel-Zuñiga, Oriol
  • Tinahones, Francisco Jose
  • Gonzalez-Guardia, Lorena
  • Malagon, Maria M
  • Bellido-Muñoz, Enrique
  • Ordovas, Jose M
  • Perez-Jimenez, Francisco
  • Lopez-Miranda, Jose
  • Perez-Martinez, Pablo
  • 1 Lipids and Atherosclerosis Unit, IMIBIC/Reina Sofia University Hospital/University of Cordoba, Cordoba, Spain; CIBER Fisiopatologia Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. , (Spain)
Type
Published Article
Journal
Molecular Nutrition & Food Research
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jul 01, 2014
Volume
58
Issue
7
Pages
1519–1527
Identifiers
DOI: 10.1002/mnfr.201300723
PMID: 24753491
Source
Medline
Keywords
License
Unknown

Abstract

These results suggest that the rs1800629 at the tumor necrosis factor alpha gene interacts with MedDiet to influence TG metabolism and inflammation status in MetS subjects. Understanding the role of gene-diet interactions may be the best strategy for personalized treatment of MetS.

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