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[Polymorphism studies of angiotensin converting enzyme gene in chronic glomerulonephritis].

Authors
  • Kutyrina, I M
  • Tareeva, I E
  • Nosikov, V V
  • Kamyshova, E S
  • Gorashko, N M
  • Chistiakov, D A
  • Okonova, E B
  • Troepol'skaia, O V
Type
Published Article
Journal
Terapevticheskiĭ arkhiv
Publication Date
Jan 01, 1999
Volume
71
Issue
6
Pages
30–34
Identifiers
PMID: 10420452
Source
Medline
License
Unknown

Abstract

Relations between ACE gene polymorphism and genetic predisposition to CGN were not found. Patients with genotype II were most sensitive to IACE and cosaar treatment. Lack of an early anti proteinuric response in homozygotes DD does not determine effectiveness of long-term IACE treatment and should not be a reason for the above drug discontinuation.

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