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Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy.

Authors
  • Kangas-Kontio, T
  • Vavuli, S
  • Kakko, S J
  • Penna, J
  • Savolainen, E-R
  • Savolainen, M J
  • Liinamaa, M Johanna
Type
Published Article
Journal
British Journal of Ophthalmology
Publisher
BMJ
Publication Date
Oct 01, 2009
Volume
93
Issue
10
Pages
1401–1406
Identifiers
DOI: 10.1136/bjo.2009.159012
PMID: 19628492
Source
Medline
License
Unknown

Abstract

In conclusion, the studied VEGF SNPs were not associated with the risk of diabetic retinopathy, and so it is unlikely that the VEGF gene is a major locus determining the risk of diabetic retinopathy. A statistically significant association of MnSOD Ala16Val polymorphism with diabetic retinopathy was found.

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