Affordable Access

Polychlorinated biphenyl residues in food and human milk: determination of co-planar and mono-ortho substituted congeners.

Authors
Type
Published Article
Journal
Zeitschrift für Lebensmittel-Untersuchung und -Forschung
Publication Date
Volume
196
Issue
5
Pages
435–440
Identifiers
PMID: 8511976
Source
Medline
License
Unknown

Abstract

An analytical method is described for determining the residues of coplanar as well as mono-ortho substituted PCB congeners both exhibiting toxicological relevance, in foods of animal origin and in human milk. The unsophisticated procedure, convenient for routine analyses, includes the extraction of lipids, clean-up steps using liquid/liquid partition and column chromatography, fractionation of the congeners using HPLC on a special carbon column with an optimal gradient elution, and capillary column gas chromatography with electron capture or mass spectrometric detection. As preliminary results indicate, the low-chlorinated PCB technical products contribute more to the actual contamination of environment and foods than has been estimated so far. Obviously the co-planar congeners are accumulated during the food chain in a portion different from that found for the other congeners.

Statistics

Seen <100 times