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Poly(lactide-co-glycolide) nanocapsules containing benzocaine: influence of the composition of the oily nucleus on physico-chemical properties and anesthetic activity.

Authors
  • de Melo, Nathalie Ferreira Silva
  • Grillo, Renato
  • Guilherme, Viviane Aparecida
  • de Araujo, Daniele Ribeiro
  • de Paula, Eneida
  • Rosa, André Henrique
  • Fraceto, Leonardo Fernandes
Type
Published Article
Journal
Pharmaceutical Research
Publisher
Springer-Verlag
Publication Date
Aug 01, 2011
Volume
28
Issue
8
Pages
1984–1994
Identifiers
DOI: 10.1007/s11095-011-0425-6
PMID: 21472490
Source
Medline
License
Unknown

Abstract

Results from our study provide useful perspectives on selection of the primary materials needed to produce suspensions of polymeric nanocapsules able to act as carriers of BZC, with potential future application in the treatment of pain.

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