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Pneumocystis.

Authors
  • Gigliotti, Francis1
  • Limper, Andrew H2
  • Wright, Terry1
  • 1 Department of Pediatrics, University of Rochester Medical School, Rochester, New York 14642.
  • 2 Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905.
Type
Published Article
Journal
Cold Spring Harbor Perspectives in Medicine
Publisher
Cold Spring Harbor Laboratory
Publication Date
Nov 03, 2014
Volume
4
Issue
12
Identifiers
DOI: 10.1101/cshperspect.a019828
PMID: 25367973
Source
Medline
License
Unknown

Abstract

Since its initial misidentification as a trypanosome some 100 years ago, Pneumocystis has remained recalcitrant to study. Although we have learned much, we still do not have definitive answers to such basic questions as, where is the reservoir of infection, how does Pneumocystis reproduce, what is the mechanism of infection, and are there true species of Pneumocystis? The goal of this review is to provide the reader the most up to date information available about the biology of Pneumocystis and the disease it produces.

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