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PNA biosensors for nucleic acid detection.

Authors
  • Wang, J1
  • 1 Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA. , (Mexico)
Type
Published Article
Journal
Current issues in molecular biology
Publication Date
Jan 01, 1999
Volume
1
Issue
1-2
Pages
117–122
Identifiers
PMID: 11475696
Source
Medline
License
Unknown

Abstract

Biosensor devices, based on the conversion of nucleic acid recognition reactions into useful electrical signals, offer considerable promise for DNA diagnostics. The unique hybridization properties of solution-phase PNA can be extrapolated onto transducer surfaces in connection with the design of remarkably specific DNA biosensors. This article reviews the development of PNA biosensors, and discusses common PNA-biosensing protocols along with their prospects in DNA biosensor technology.

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