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Platelet aggregation in patients treated with diflunisal.

Authors
  • Ghosh, M L
  • Tingle, A
Type
Published Article
Journal
Current medical research and opinion
Publication Date
Jan 01, 1980
Volume
6
Issue
7
Pages
510–512
Identifiers
PMID: 7363651
Source
Medline
License
Unknown

Abstract

The effect of the non-steroidal analgesic diflunisal on platelet aggregation and clinical haemorrhage at a dosage 250 mg twice or 3-times daily, sufficient to relieve musculo-skeletal pain and other painful conditions, was studied in 15 patients and 5 normal subjects. Platelet aggregation was carried out with ADP and collagen before and during treatment with diflunisal. The results indicated that diflunisal is an effective analgesic with no significant adverse effect on platelet function or clinical bleeding.

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