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Platelet-activating factor analogs. II. Synthesis of the 1-O-(4-decyloxymethylphenyl)- and 1-O-(4-decyloxyphenylmethyl) analogs.

Authors
  • Anderson, R C
  • Reitter, B E
  • Winslow, C M
Type
Published Article
Journal
Chemistry and Physics of Lipids
Publisher
Elsevier
Publication Date
Jan 01, 1986
Volume
39
Issue
1-2
Pages
73–82
Identifiers
PMID: 3948294
Source
Medline
License
Unknown

Abstract

1-O-(4-Decyloxymethylphenyl)- and 1-O-(4-decyloxyphenylmethyl)-2-O-acetyl-glycero-3-phosphorylcholin e were synthesized from 2,2-dimethyl-1,3-dioxolane-4-methanol. The utility of a 2-O-tetrahydropyranyl ether as a protecting group and its facile removal in the presence of a 3-phosphorylcholine is illustrated.

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