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Plasma substance P levels in fibrositis.

Authors
Type
Published Article
Journal
The Journal of rheumatology
Publication Date
Volume
15
Issue
12
Pages
1802–1803
Identifiers
PMID: 2466119
Source
Medline
License
Unknown

Abstract

The mechanism of pain in the fibrositis syndrome is unknown. We measured plasma levels of substance P in 32 patients with fibrositis and 26 sex and age matched controls using a radioimmunoassay. The mean plasma level of substance P in the patients with fibrositis was 371 +/- 91 pg/ml and in controls 397 +/- 84 pg/ml (p = NS). We conclude that determination of plasma levels of substance P in fibrositis is of no diagnostic value. This does not exclude the possible role of substance P as a neurotransmitter in the fibrositis syndrome.

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