Affordable Access

deepdyve-link
Publisher Website

Plasma membrane growth during the cell cycle: unsolved mysteries and recent progress.

Authors
Type
Published Article
Journal
Current Opinion in Cell Biology
Publisher
Elsevier
Volume
24
Issue
6
Pages
845–851
Identifiers
DOI: 10.1016/j.ceb.2012.10.008
Source
UCSC Cancer biomedical-ucsc
License
Unknown

Abstract

Growth of the plasma membrane is as fundamental to cell reproduction as DNA replication, chromosome segregation and ribosome biogenesis, yet little is known about the underlying mechanisms. Membrane growth during the cell cycle requires mechanisms that control the initiation, location, and extent of membrane growth, as well as mechanisms that coordinate membrane growth with cell cycle progression. Recent experiments have established links between membrane growth and core cell cycle regulators. Further analysis of these links will yield insights into conserved and fundamental mechanisms of cell growth. A better understanding of the post-Golgi pathways by which membrane growth occurs will be essential for future progress.

Report this publication

Statistics

Seen <100 times