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Plasma levels of dehydroepiandrosterone and 17 beta-estradiol after intramuscular administration of Gynodian-Depot in 3 women.

Authors
  • Düsterberg, B
  • Wendt, H
Type
Published Article
Journal
Hormone research
Publication Date
Jan 01, 1983
Volume
17
Issue
2
Pages
84–89
Identifiers
PMID: 6220949
Source
Medline
License
Unknown

Abstract

Gynodian-Depot is well suited for treatment of the characteristic symptoms accompanying the menopause in women. The plasma levels of prasterone and 17 beta-estradiol after intramuscular injection of Gynodian-Depot in women were studied using a radioimmunological method. The maximum active ingredient concentrations were found in the plasma of the subjects only a few days after administration. The depot action lasted on an average 14 days (17 beta-estradiol) and 18 days (prasterone) after administration, respectively. Prasterone enanthate is completely hydrolysed into the free steroid and the fatty acid.

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