Determination of the plasma fibrinogen concentration was found to be particularly useful in detecting inflammatory diseases. The highest levels were observed in inflammatory lesions of serous surfaces and in endocarditis. Plasma fibrinogen levels correlated with the severity of the disease: levels of 1,000 mg per 100 ml or more reflected a prognosis ranging from poor to bad.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6506055