Plasma exchange and chelator therapy rescues acute liver failure in Wilson disease without liver transplantation.
Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan.
Department of Transplantation and Pediatric Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan.
- Published Article
Hepatology research : the official journal of the Japan Society of Hepatology
- Publication Date
It is better to undergo LT for WD patients with a NWI score ≥ 11, however, there is a possibility of remission by plasma exchange and medical therapy even without LT. WD patients with a NWI score ≥ 11can be rescued by conservative therapy when the ALF of WD does not present with ALF and hepatic encephalopathy. Therefore, ALF with hepatic encephalopathy itself is an indication for LT in WD.
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This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/27007780