Affordable Access

deepdyve-link
Publisher Website

Plasma exchange and chelator therapy rescues acute liver failure in Wilson disease without liver transplantation.

Authors
  • Kido, Jun1
  • Matsumoto, Shirou1
  • Momosaki, Ken1
  • Sakamoto, Rieko1, 2
  • Mitsubuchi, Hiroshi1
  • Inomata, Yukihiro2
  • Endo, Fumio1
  • Nakamura, Kimitoshi1
  • 1 Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan. , (Japan)
  • 2 Department of Transplantation and Pediatric Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto City, Japan. , (Japan)
Type
Published Article
Journal
Hepatology research : the official journal of the Japan Society of Hepatology
Publication Date
March 2017
Volume
47
Issue
4
Pages
359–363
Identifiers
DOI: 10.1111/hepr.12711
PMID: 27007780
Source
Medline
Keywords
License
Unknown

Abstract

It is better to undergo LT for WD patients with a NWI score ≥ 11, however, there is a possibility of remission by plasma exchange and medical therapy even without LT. WD patients with a NWI score ≥ 11can be rescued by conservative therapy when the ALF of WD does not present with ALF and hepatic encephalopathy. Therefore, ALF with hepatic encephalopathy itself is an indication for LT in WD.

Report this publication

Statistics

Seen <100 times