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Plasma cytokine levels in patients with severe burn injury--with reference to the relationship between infection and prognosis.

Authors
  • Yamada, Y
  • Endo, S
  • Inada, K
Type
Published Article
Journal
Burns
Publisher
Elsevier
Publication Date
Dec 01, 1996
Volume
22
Issue
8
Pages
587–593
Identifiers
PMID: 8982534
Source
Medline
License
Unknown

Abstract

Blood levels of various cytokines were determined in patients with burn injury immediately after the accident, and the relationship between cytokines and morbid condition was investigated. There was almost no marked elevation of cytokines in the early stage of burn injury. Throughout the entire course, tumour necrosis factor alpha, interleukin 6 and interleukin 8, as cytokines, showed high levels in patients with burn injury associated with sepsis and those who died. These levels well reflected the severity in the phase complicated with sepsis.

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