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Plasma carotenoids and the prevalence of adenomatous polyps of the distal colon and rectum.

Authors
Type
Published Article
Journal
American Journal of Epidemiology
0002-9262
Publisher
Oxford University Press
Publication Date
Volume
145
Issue
6
Pages
552–557
Identifiers
PMID: 9063346
Source
Medline
License
Unknown

Abstract

In a case-control study, the authors investigated relations between plasma carotenoid concentrations and the prevalence of colorectal adenomatous polyps (precursors to colorectal cancer) in residents of Los Angeles County and Orange County, California, from 1991 through 1993. Plasma concentrations of six carotenoids were compared in 472 asymptomatic cases with a first-time diagnosis of at least one adenomatous polyp of the distal colon or rectum and 502 matched controls. Odds ratios adjusted for age, sex, smoking, alcohol intake, and energy, saturated fat, and fruit and vegetable intake revealed no associations between any of the individual carotenoids and polyp prevalence or between total carotenoids and polyp prevalence.

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