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Plasma 8-isoprostane levels are associated with endothelial dysfunction in resistant hypertension.

Authors
  • de Faria, Ana Paula Cabral1
  • Fontana, Vanessa1
  • Modolo, Rodrigo1
  • Barbaro, Natália Ruggeri1
  • Sabbatini, Andréa Rodrigues1
  • Pansani, Isabella Fagian1
  • Ferreira-Melo, Silvia E1
  • Moreno, Heitor2
  • 1 Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. , (Brazil)
  • 2 Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. Electronic address: [email protected] , (Brazil)
Type
Published Article
Journal
Clinica chimica acta; international journal of clinical chemistry
Publication Date
Jun 10, 2014
Volume
433
Pages
179–183
Identifiers
DOI: 10.1016/j.cca.2014.03.009
PMID: 24657423
Source
Medline
Keywords
License
Unknown

Abstract

RHTN showed markedly higher oxidative stress measured by 8-isoprostane, compared to HT patients. Taken together, our findings suggest the involvement of oxidative stress in endothelial function in RHTN.

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