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PITX2 gain-of-function induced defects in mouse forelimb development.

Authors
  • Holmberg, Johan
  • Ingner, Gorel
  • Johansson, Curt
  • Leander, Peter
  • Hjalt, Tord A
Type
Published Article
Journal
BMC Developmental Biology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2008
Volume
8
Pages
25–25
Identifiers
DOI: 10.1186/1471-213X-8-25
PMID: 18312615
Source
Medline
License
Unknown

Abstract

Taken together, the tendon, muscle, and bone anomalies further support a role of Pitx2 in forelimb development and may also shed light on the interaction between the skeletal elements and muscles of the limb during embryogenesis.

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