Affordable Access

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption.

Authors
  • Sansone, Andrea1
  • Sansone, Massimiliano1
  • Vena, Walter2
  • Tedone, Radha3
  • Romanelli, Francesco1
  • 1 Department of Experimental Medicine, "Sapienza" University of Rome, Viale Regina Elena 324, Rome 00161, Italy, Italy. , (Italy)
  • 2 Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milano, Italy. , (Italy)
  • 3 Pediatric Surgery Unit, Department of Pediatrics and Infantile Neuropsychiatry, Azienda Policlinico Umberto I, Sapienza University of Rome, Rome, Italy. , (Italy)
Type
Published Article
Journal
Neuro endocrinology letters
Publication Date
Aug 05, 2017
Volume
38
Issue
4
Pages
243–247
Identifiers
PMID: 28871708
Source
Medline
License
Unknown

Abstract

We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia. We performed thyroxine absorption tests to diagnose the malabsorption and to evaluate the best therapeutic intervention. Once assessed a correct therapy lowering TSH, we observed the regression of pituitary mass confirming our diagnosis of secondary pituitary hyperplasia. We suggest to evaluate any possible reason for thyroxine malabsorption and to consider the hypothesis of pituitary hyperplasia in the presence of pituitary mass together with overt hypothyroidism.

Report this publication

Statistics

Seen <100 times