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Pituitary hormone dysfunction after proton beam radiation therapy in children with brain tumors.

Authors
Type
Published Article
Journal
Endocrine Practice
1934-2403
Publisher
American Association of Clinical Endocrinologists
Publication Date
Volume
17
Issue
6
Pages
891–896
Identifiers
DOI: 10.4158/EP10391.OR
PMID: 21613054
Source
Medline
License
Unknown

Abstract

A high rate of endocrine sequelae was seen in our study. Children with brain tumors treated with conventional plus PB irradiation developed endocrine dysfunction faster and received a higher radiation dose than those receiving PB radiotherapy only. Prior surgical treatment and chemotherapy were additional risk factors. Large prospective studies are needed to evaluate further the incidence of endocrine sequelae after PB irradiation in children.

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