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Pituitary apoplexy and panhypopituitarism following acute leptospirosis

Authors
  • Gohil, Jaypalsinh1
  • Gowda, Arun1
  • George, Tobin1
  • Easwer, H. V.1
  • George, Alexander2
  • Nair, Prakash1
  • 1 Sree Chitra Tirunal Institute for Medical Sciences and Technology,
  • 2 Holy Cross Hospital, Kottiyam, Kerala India
Type
Published Article
Journal
Pituitary
Publisher
Springer-Verlag
Publication Date
May 21, 2021
Pages
1–5
Identifiers
DOI: 10.1007/s11102-021-01156-1
PMID: 34021443
PMCID: PMC8139373
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown

Abstract

Leptospirosis is a common tropical febrile illness which may manifest with the hepatorenal syndrome and systemic hemorrhagic manifestations. Pituitary apoplexy is a rare but life-threatening condition characterized by a hemorrhage within the pituitary gland or a pituitary adenoma. Apoplexy is very rarely associated with some inducing events such as infectious diseases such as dengue hemorrhagic fever, Hantaan virus, Puumala virus have also been reported to cause pituitary apoplexy. We present the first case of pituitary apoplexy in a patient who was being treated for leptospirosis and discuss the possible mechanisms of apoplexy in the scenario presented. We also review other reports of infectious causes that may result in pituitary apoplexy.

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