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Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats.

Authors
  • Ko, Gang Jee
  • Kang, Young Sun
  • Han, Sang Youb
  • Lee, Mi Hwa
  • Song, Hye Kyoung
  • Han, Kum Hyun
  • Kim, Hyoung Kyu
  • Han, Jee Young
  • Cha, Dae Ryong
Type
Published Article
Journal
Nephrology Dialysis Transplantation
Publisher
Oxford University Press
Publication Date
Sep 01, 2008
Volume
23
Issue
9
Pages
2750–2760
Identifiers
DOI: 10.1093/ndt/gfn157
PMID: 18388116
Source
Medline
License
Unknown

Abstract

These data suggest that pioglitazone not only improves insulin resistance, glycaemic control and lipid profile, but also ameliorates renal injury through an anti-inflammatory mechanism in type 2 diabetic rats.

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