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A pilot study: subclinical hypothyroidism and free thyroid hormone measurement by immunoassay and mass spectrometry.

Authors
  • Gounden, Verena1
  • Jonklaas, Jacqueline2
  • Soldin, Steven J3
  • 1 Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD, USA.
  • 2 Division of Endocrinology, Georgetown University Medical Center, Washington, DC, USA.
  • 3 Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD, USA; Division of Endocrinology, Georgetown University Medical Center, Washington, DC, USA. Electronic address: [email protected]
Type
Published Article
Journal
Clinica chimica acta; international journal of clinical chemistry
Publication Date
Mar 20, 2014
Volume
430
Pages
121–124
Identifiers
DOI: 10.1016/j.cca.2013.12.034
PMID: 24389098
Source
Medline
Keywords
License
Unknown

Abstract

Our findings indicate that the direct analogue immunoassay method for FT4 measurement results in a significant proportion of patients being misclassified as having subclinical hypothyroidism.

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