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Physiology and pathology of the oesophagus in the elderly patient.

Authors
  • Lock, G
Type
Published Article
Journal
Best Practice & Research Clinical Gastroenterology
Publisher
Elsevier
Publication Date
Dec 01, 2001
Volume
15
Issue
6
Pages
919–941
Identifiers
PMID: 11866485
Source
Medline
License
Unknown

Abstract

In the 1960s, the term 'presbyoesophagus' was introduced for what were felt to be the characteristics of the oesophagus in old age. Since then a number of sophisticated studies using modern manometric, radiological, pH-metric or endoscopic equipment have been performed to better study this subject. Although results in some aspects are still contradictory, these studies have provided us with some more detailed information on the physiology of the ageing oesophagus. Beginning with an overview of what is currently known and discussed about age-induced physiological changes in oesophageal function, this review will then focus on specific problems of oesophagus-related diseases in the elderly. The main topics discussed will include presentation, diagnosis and treatment of primary and secondary motility disorders, oesophageal manifestations of neuromuscular and neurological disease, gastro-oesophageal reflux disease and oesophageal cancer in the elderly.

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