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[The physiological importance of cervical secretion and its role in reproduction].

Authors
  • Chretien, F C
Type
Published Article
Journal
Contraception, fertilité, sexualité
Publication Date
Jan 01, 1979
Volume
7
Issue
1
Pages
31–41
Identifiers
PMID: 12309433
Source
Medline
Keywords
License
Unknown

Abstract

The physiological importance of cervical mucus is major and essential. Sterility is often due to some kind of disorder in this short genital tract, linking the vagina with the uterine cavity. The major factors facilitating the transport of spermatozoa into the uterine cavity are: 1) protection against the strong acid conditions of the vagina; 2) penetrability of the mucus only during the days in which impregnantion is possible; 3) asepsis of the uterine cavity and of the upper genital tract by means of lactoferrine, peroxidase and lysozyme; 4) selection of spermatozoa, favoring the strongest and most mobile ones; 5) selection of spermatozoa carrying the "Y" chromosome; 6) providing spermatozoa with the best possible milieu from which to draw energy; 7) protection of the male gametes against eventual phagocytosis from leucocytes; 8) creation of an intracervical reserve of spermatozoa. All these factors contribute to favor the meeting of the gametes at the best possible moment, in the best possible conditions.

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