Affordable Access

Physical activity interferes with the immunomodulatory effect of the antineoplastic drug NSC631570.

Authors
Type
Published Article
Journal
Current pharmaceutical biotechnology
Publication Date
Volume
16
Issue
1
Pages
49–59
Identifiers
PMID: 25395210
Source
Medline
License
Unknown

Abstract

NSC 631570 causes M1 (N1) shift of phagocytes after in vivo introduction. Moderate physical exercise exerts a negative effect on the immunomodulatory action of NSC 631570 by abrogating M1 (N1) shift of circulating phagocytes. One of the reasons for such an effect could be an increase in PPAR-γ expression by phagocytes.

Statistics

Seen <100 times