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[Phylogenetic and molecular analysis of A/H1N1pdm influenza viruses isolated in the epidemic season 2012/2013 from hospitalised patients with -symptoms of influenza-like illness].

Authors
  • Nagy, A
  • Jiřincová, H
  • Havlíčková, M
  • Džupová, O
  • Herrmannová, K
  • Trojánek, M
  • Kynčl, J
  • Blechová, Z
  • Marešová, V
Type
Published Article
Journal
Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceské lékarské spolecnosti J.E. Purkyne
Publication Date
Jun 01, 2014
Volume
63
Issue
2
Pages
83–87
Identifiers
PMID: 25025668
Source
Medline
License
Unknown

Abstract

All A/H1N1pdm isolates from the epidemic season 2012/2013 in the Czech Republic formed a phenotypically uniform group. At the nucleotide level, the divergence was relatively more pronounced and H1 sublineages and discrete genotypes were possible to identify. H1 molecules were highly identical to those of the vaccine strain A/California/7/2009 (H1N1) which showed that the current vaccine was protective enough. All strains were sensitive to oseltamivir; however, the selection of oseltamivir resistant N1 subpopulations was observed.

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