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Phosphonates and their degradation by microorganisms.

Authors
  • Kononova, S V
  • Nesmeyanova, M A
Type
Published Article
Journal
Biochemistry. Biokhimii︠a︡
Publication Date
Feb 01, 2002
Volume
67
Issue
2
Pages
184–195
Identifiers
PMID: 11952414
Source
Medline
License
Unknown

Abstract

Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Wide occurrence of phosphonates among xenobiotics polluting the environment has aroused interest in pathways and mechanisms of their biodegradation. Only procaryotic microorganisms and the lower eucaryotes are capable of phosphonate biodegradation via several pathways. Destruction of the non-activated C-P bond by the C-P lyase pathway is of fundamental importance, and understanding of the process is a basic problem of biochemistry and physiology of microorganisms. This review offers analysis of available data on phosphonate-degrading microorganisms, degradation pathways, and genetic and physiological regulation of this process.

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