Affordable Access

Phosphoinositides in yeast: genetically tractable signalling.

Authors
  • Wera, S
  • Bergsma, J C
  • Thevelein, J M
Type
Published Article
Journal
FEMS yeast research
Publication Date
Apr 01, 2001
Volume
1
Issue
1
Pages
9–13
Identifiers
PMID: 12702458
Source
Medline
License
Unknown

Abstract

Research on signalling through phosphoinositides has made tremendous advances over the last few years. Studies with budding yeast (Saccharomyces cerevisiae) combine the advantage of a eukaryotic system with those of a rapidly growing, genetically modifiable and tractable organism of which the genome is fully sequenced. Hence, despite some differences in phosphoinositide signalling between mammals and yeast (e.g. the absence of PtdIns(3,4,5)P(3)), this model organism is at the forefront of phosphoinositide research. In this review we will focus on recent discoveries concerning the role of phosphoinositides in yeast.

Report this publication

Statistics

Seen <100 times