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[Phosphohexose isomerase in psoriasis].

Authors
  • Vignale, R A
  • Espasandiń, J
  • Lasalvia, E
  • Borras, A
Type
Published Article
Journal
Medicina cutánea ibero-latino-americana
Publication Date
Jan 01, 1982
Volume
10
Issue
1
Pages
15–20
Identifiers
PMID: 6214672
Source
Medline
License
Unknown

Abstract

--The authors study in psoriasis an enzyme of the glucolytic way, the Phospho-hexose-isomerase. --They find significant high levels in blood and damaged skin, while these were "normal" in healthy skin. --Phospho-hexose-isomerase acts as a biological marker in psoriasis, and acquires the significance of an active cellular proliferation. --The highest values are those of the erythrodermaes which become normal with clinical involution. --The authors suggest that psoriasis, by an exaggerated cellular division inhibition mechanism, metabolism is deviated in order to bring the energetic elements and substrate to form the new cell. --Phospho-hexose-isomerase is not specific of the malignant process.

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