Affordable Access

Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence.

Authors
  • Tugnoli, V
  • Poerio, A
  • Tosi, M R
Type
Published Article
Journal
Oncology reports
Publication Date
Aug 01, 2004
Volume
12
Issue
2
Pages
353–356
Identifiers
PMID: 15254701
Source
Medline
License
Unknown

Abstract

This study presents a multinuclear (1H, 13C and 31P) magnetic resonance spectroscopy characterization of the total lipid fraction extracted from different regions of a human kidney affected by a clear cell renal carcinoma. It was thus possible to demonstrate that cholesteryl esters and phosphatidylcholine are markers of the tumor infiltration, histologically confirmed, in the kidney medulla. The tumor tissue contains twice the amount of phosphatidylcholine compared to normal cortex. The results appear relevant in light of new clinical applications based on the biochemical composition of human tissues.

Report this publication

Statistics

Seen <100 times