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Phenotypic alteration in malignant transformation of colonic villous tumours: with special reference to a comparison with tubular tumours.

Authors
  • Takata, M
  • Yao, T
  • Nishiyama, K-I
  • Nawata, H
  • Tsuneyoshi, M
Type
Published Article
Journal
Histopathology
Publication Date
Oct 01, 2003
Volume
43
Issue
4
Pages
332–339
Identifiers
PMID: 14511251
Source
Medline
License
Unknown

Abstract

There were significant differences in the phenotypic expression of adenoma and adenocarcinoma between villous and tubular tumours, respectively. Villous tumours have a pathway of malignant transformation different from that of tubular tumours. Because of biological differences, colorectal villous tumours should be distinguished from tubular neoplasia. The analysis of the phenotype of colorectal neoplasms is useful for the evaluation of tumour progression.

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