Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report.
1Department of Thoracic/Head and Neck Medical Oncology, Thoracic/Cardiovascular Surgery, Radiation Therapy, Pathology, Radiology, and Biostatistics, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA. [email protected]
The use of induction chemotherapy to optimize surgical resectability of thymoma followed by radiation therapy and consolidation chemotherapy lead to good control of residual disease and high overall survival rates. We believe that this combined multidisciplinary approach prolongs lives and may cure locally advanced unresectable malignant thymomas. Future prospective multi-institutional studies are needed to further verify or define the best treatment for this patient population.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15140551