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PharmGKB: the Pharmacogenetics Knowledge Base.

Authors
  • M, Hewett
  • De, Oliver
  • Dl, Rubin
  • Kl, Easton
  • Josh Stuart
  • Rb, Altman
  • Te, Klein
Type
Published Article
Journal
Nucleic Acids Research
Publisher
Oxford University Press
Volume
30
Issue
1
Pages
163–165
Source
UCSC Stem Cell biomedical-ucsc
License
Unknown

Abstract

The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.

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