PharmGKB: the Pharmacogenetics Knowledge Base.
- Authors
- Type
- Published Article
- Journal
- Nucleic Acids Research
- Publisher
- Oxford University Press
- Volume
- 30
- Issue
- 1
- Pages
- 163–165
- Source
- UCSC Stem Cell biomedical-ucsc
- License
- Unknown
Abstract
The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.