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Pharmacotherapy for inappropriate sexual behaviors in dementia: a systematic review of literature.

Authors
  • Ozkan, Banu1
  • Wilkins, Kirsten
  • Muralee, Sunanda
  • Tampi, Rajesh R
  • 1 Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA.
Type
Published Article
Journal
American journal of Alzheimer's disease and other dementias
Publication Date
Jan 01, 2008
Volume
23
Issue
4
Pages
344–354
Identifiers
DOI: 10.1177/1533317508318369
PMID: 18509106
Source
Medline
License
Unknown

Abstract

The aim of this study is to systematically review the published literature on pharmacotherapy for inappropriate sexual behaviors in dementia. Literature search of the 5 databases (PubMed, MEDLINE, EMBASE, PsychINFO, and COCHRANE collaboration) and the analysis of the data available for the pharmacotherapeutic treatments of inappropriate sexual behaviors in dementia were carried out. There are no published randomized controlled trials of pharmacotherapy for inappropriate sexual behaviors in dementia, but available data form uncontrolled trials, case series, and individual case reports suggest efficacy for antidepressants, antipsychotics, mood stabilizers, hormonal agents, cimetidine, and pindolol for the treatment of these behaviors. Although there are no controlled data for the treatment of inappropriate sexual behaviors in dementia, available data suggest efficacy for some commonly used pharmacotherapeutic agents.

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