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Pharmacological characteristics of a novel, recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).

Authors
  • Zollner, S
  • Schuermann, D
  • Raquet, E
  • Mueller-Cohrs, J
  • Weimer, T
  • Pragst, I
  • Dickneite, G
  • Schulte, S
Type
Published Article
Journal
Journal of thrombosis and haemostasis : JTH
Publication Date
Feb 01, 2014
Volume
12
Issue
2
Pages
220–228
Identifiers
DOI: 10.1111/jth.12477
PMID: 24641308
Source
Medline
Keywords
License
Unknown

Abstract

These studies indicate that the longer t(½) of rVIIa-FP compared with rFVIIa translates into extended activity. These findings suggest that rVIIa-FP has the potential to be administered less frequently than rFVIIa-containing concentrates in clinical use.

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