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Pharmacologic therapeutic window of pramiracetam demonstrated in behavior, EEG, and single neuron firing rates.

Authors
  • Poschel, B P
  • Ho, P M
  • Ninteman, F W
  • Callahan, M J
Type
Published Article
Journal
Experientia
Publication Date
Sep 15, 1985
Volume
41
Issue
9
Pages
1153–1156
Identifiers
PMID: 4043326
Source
Medline
License
Unknown

Abstract

Following oral or intravenous administration, a representative cognition activator drug, pramiracetam sulfate, is shown to have a pharmacologic therapeutic window at three different levels of study: learned behavior, gross EEG activity of the frontal cortex and hippocampus, and firing rate of single hippocampal neurons.

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