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Pharmacokinetics of Itraconazole Oral Solution in Neutropenic Children during Long-Term Prophylaxis

Authors
Publisher
American Society for Microbiology
Publication Date
Source
PMC
Keywords
  • Pharmacology
Disciplines
  • Pharmacology

Abstract

We investigated the pharmacokinetics and safety of an oral solution of itraconazole in two groups of neutropenic children stratified by age. Effective concentrations of itraconazole in plasma were reached quickly and maintained throughout treatment. The results indicate a trend toward higher concentrations of itraconazole in plasma in older children.

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