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Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model

Authors
  • Cheema, Amrita K.
  • Mehta, Khyati Y.
  • Santiago, Paola T.
  • Fatanmi, Oluseyi O.
  • Kaytor, Michael D.
  • Singh, Vijay K.
Publication Date
Mar 12, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

with the po route showing fewer metabolic alterations. Taken together, our results suggest that the administration of BIO 300 results in metabolic shifts that could provide an overall advantage to combat radiation injury. This initial assessment also highlights the utility of metabolomics and lipidomics to determine the underlying physiological mechanisms involved in the radioprotective efficacy of BIO 300.

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