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[PET as a tool in pharmacologic development].

Authors
  • Bergström, M1
  • Hartvig, P
  • Långström, B
  • 1 Uppsala Universitet PET-centrum.
Type
Published Article
Journal
Nordisk medicin
Publication Date
Sep 01, 1998
Volume
113
Issue
7
Pages
226–229
Identifiers
PMID: 9755618
Source
Medline
Language
Swedish
License
Unknown

Abstract

Positron emission tomography (PET) allows the in vivo recording of tracer compounds with respect to anatomical distribution, time course and absolute concentration. These features has proven of great value in drug development, especially in the phase of early clinical trials. PET can be used to assess the tissue kinetics of a new drug, or to evaluate a drugs interaction with a target system and thereby aid in decisions regarding dosing regimes.

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