[Persistent influenza virus infection in a MDCK cell culture].
- Published Article
- Publication Date
Jan 01, 1984
A model of persistent influenza infection (PII) induced by influenza A/Victoria/35/72 (H3N2) virus in MDCK cell culture has been constructed. The model was observed for 165 days. It was characterized by the lack of visible signs of virus reproduction, a low number of antigen-containing cells (0.02-0.05%), irregular virus isolation (at 20, 28, 32, 44, 52, 62, 92, 135, 148, 158 days after primary inoculation) which was possible only with special methods. Interferon and DIP were found not to be the factors responsible for maintenance of PII in MDCK culture.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6516326