[Peroxisome proliferator activated receptor gamma coactivator-1 induces apoptosis in human epithelial ovarian cancer cells].
- Published Article
Zhonghua yi xue za zhi
- Publication Date
May 29, 2007
PGC-1alpha induces apoptosis in epithelial ovarian cancer cells in vitro, which may be a result of up-regulation of the pro-apoptotic gene Bax and down-regulation of the anti-apoptotic gene Bcl-2. And over-expression of PGC-1alpha results in no apoptosis in CHO.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/17785072