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[Peroxisome proliferator activated receptor gamma coactivator-1 induces apoptosis in human epithelial ovarian cancer cells].

Authors
  • Ba, Yi
  • Zhang, Yan
  • Zhang, Chen-yu
Type
Published Article
Journal
Zhonghua yi xue za zhi
Publication Date
May 29, 2007
Volume
87
Issue
20
Pages
1430–1433
Identifiers
PMID: 17785072
Source
Medline
License
Unknown

Abstract

PGC-1alpha induces apoptosis in epithelial ovarian cancer cells in vitro, which may be a result of up-regulation of the pro-apoptotic gene Bax and down-regulation of the anti-apoptotic gene Bcl-2. And over-expression of PGC-1alpha results in no apoptosis in CHO.

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