Affordable Access

Periventricular white matter lucencies in senile dementia of the Alzheimer type and in normal aging.

Authors
  • Rezek, D L
  • Morris, J C
  • Fulling, K H
  • Gado, M H
Type
Published Article
Journal
Neurology
Publication Date
Aug 01, 1987
Volume
37
Issue
8
Pages
1365–1368
Identifiers
PMID: 3614659
Source
Medline
License
Unknown

Abstract

The significance of periventricular lucencies in the white matter on CT in demented patients is not understood. We studied the relationship of these changes to mental status of subjects with senile dementia of the Alzheimer type. A semiquantitative method showed more numerous and extensive lucencies in demented than in healthy elderly. Neuropathologic examination of five subjects with these changes and confirmed Alzheimer's disease revealed diffuse white matter pallor without infarction. There were no hypertensive vascular changes, although limited hyaline thickening was present.

Report this publication

Statistics

Seen <100 times