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Peritoneal fluid and solute transport with different polyglucose formulations.

Authors
  • Wang, T
  • Heimbürger, O
  • Cheng, H H
  • Bergström, J
  • Lindholm, B
Type
Published Article
Journal
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Publication Date
Jan 01, 1998
Volume
18
Issue
2
Pages
193–203
Identifiers
PMID: 9576369
Source
Medline
License
Unknown

Abstract

Our results suggest that, although there was an initial decrease in the intraperitoneal dialysate volume, significant amounts of fluid can be removed by polyglucose solution during a single 4-hour dwell in rats, despite the low osmolality of the solution. The positive fluid removal induced by the PG solution is partially due to the lower fluid absorption rate associated with this solution and may, to some extent, also be due to the degradation of glucose polymer within the peritoneal cavity, resulting in increased dialysate osmolality. The addition of glucose to the polyglucose solution does not seem to improve ultrafiltration in a 4-hour dwell in the rat model. However, the peritoneal fluid absorption rate may be increased, and peritoneal transport of glucose and sodium may be altered, by adding glucose to the polyglucose solution.

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